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Answering the White House call-to-action to ensure the appropriate balance between the benefits of prescribed opioids and the risks they pose.

A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction among Patients Treated with Extended-Release/Long Acting (ER/LA) Opioids for the Treatment of Chronic Pain

Although abuse and misuse of prescription opioids have increased over the past decade, there is debate about the magnitude of misuse, abuse, and addiction among patients who are treated with opioids for chronic pain. Further, although there appears to be comorbidity of opioid use disorders with other substance use and psychiatric disorders, there is insufficient data to estimate how the risk of these outcomes varies by the presence of risk factors among patients treated with opioids long-term.

This study, led by Dr. Seshadri Mudumbai, seeks to provide quantitative estimates of the serious risks of long-term use of opioid analgesics for management of chronic pain among patients prescribed extended-release/long-acting (ER/LA) opioid products.

This work is funded by Campbell Alliance (protocol PMR 3033-1 / PRM 2065-1).

Last Modified: November 5, 2019 6:33pm
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